Polycations. 17. Synthesis and properties of polycationic derivatives of carbohydrates.

نویسندگان

  • Marie Thomas
  • Diego Montenegro
  • Alejandra Castaño
  • Laura Friedman
  • Jay Leb
  • Mia Lace Huang
  • Leah Rothman
  • Heidi Lee
  • Craig Capodiferro
  • Daniel Ambinder
  • Eva Cere
  • Jessica Galante
  • JaimeLee Rizzo
  • Karin Melkonian
  • Robert Engel
چکیده

In our continuing investigation of polycationic salts for purposes of antimicrobial action, ion-channel blocking, and construction of ionic liquids, we have prepared several series of polycationic salts derived from carbohydrate precursors. These salts are currently being investigated for optimal efficacy as antibacterials and antifungals, as well as for other applications. The syntheses of such series of salts are described here along with preliminary antibacterial testing results and a discussion of their properties indicating their potential utility for several purposes.

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عنوان ژورنال:
  • Carbohydrate research

دوره 344 13  شماره 

صفحات  -

تاریخ انتشار 2009